MEPACOFEN: Comprehensive Guide to Uses, Dosage, Side Effects & More
MEPACOFEN is a widely used medication in Egypt, available in several forms and strengths. It contains Ketoprofen, a well-known nonsteroidal anti-inflammatory drug (NSAID) from the propionic acid derivatives group. MEPACOFEN is designed to relieve pain, reduce inflammation, and treat various musculoskeletal and joint conditions.
This article provides a complete, easy-to-understand overview of MEPACOFEN, including its uses, ingredients, dosage forms, side effects, and more — making it suitable for anyone looking to learn more about this medication.
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Introduction
MEPACOFEN is used to treat pain, inflammation, and swelling caused by various conditions, including arthritis, back pain, muscle strains, and injuries. It is available in capsule, tablet, and topical gel forms, offering flexible treatment options depending on the patient's needs.
It belongs to the NSAID (nonsteroidal anti-inflammatory drug) family, which means it works by reducing substances in the body that cause inflammation and pain.
The most common side effects include:
- Upset stomach
- Nausea
- Headache
Some people may experience skin reactions when using the gel form.
Patients should always follow their doctor's instructions and read the packaging carefully to avoid potential side effects or drug interactions.
Composition (Active Ingredients)
All forms of MEPACOFEN contain the active ingredient:
- Ketoprofen – an NSAID (nonsteroidal anti-inflammatory drug) that helps reduce pain and inflammation by blocking the production of prostaglandins (chemicals that cause inflammation and pain).
Forms and Strengths
| Product Name | Form | Strength | Price in Egypt (2025) |
|---|---|---|---|
| MEPACOFEN S.R. | Capsules | 100 mg | 13 EGP |
| MEPACOFEN L.A. | Tablets | 150 mg | 37 EGP |
| MEPACOFEN | Tablets | 25 mg | 6 EGP |
| MEPACOFEN Topical Gel | Gel | 2.5% | 5 EGP |
Note: Prices are current for 2025 but may change later.
Indications (Uses)
MEPACOFEN is used to relieve mild to moderate pain, swelling, and inflammation in a variety of conditions.
Common Uses
Osteoarthritis and Rheumatoid Arthritis
- Reduces joint pain, swelling, and stiffness, making daily activities easier.
Back Pain and Muscle Pain
- Helps reduce inflammation in muscles and connective tissues, offering relief after injuries or overuse.
Dental Pain
- Relieves toothaches and pain after dental procedures by reducing inflammation and sensitivity.
Menstrual Pain (Dysmenorrhea)
- Lowers prostaglandin levels, which are elevated during menstruation and cause uterine contractions and pain.
Sports Injuries
- Topical MEPACOFEN gel is ideal for sports-related injuries, including bruises, strains, and swollen joints. It targets pain locally without affecting the whole body.
Mechanism of Action
MEPACOFEN works by inhibiting an enzyme in the body called cyclooxygenase (COX), which helps produce prostaglandins. These prostaglandins are the substances that cause inflammation, pain, and fever.
When MEPACOFEN blocks this enzyme:
- Less inflammation is produced.
- Swelling goes down.
- Pain signals are reduced in the nerves.
Analogy:
Think of prostaglandins like an "alarm system" that the body sets off when there's injury or irritation. MEPACOFEN silences the alarm, helping you feel better.
Dosage
General Guidelines
Always follow the doctor's instructions or the package leaflet. Dosage varies based on the product form, age group, and condition being treated.
Adults
| Form | Strength | Typical Use |
|---|---|---|
| MEPACOFEN 25 mg Tablets | 25 mg | 2-3 times daily |
| MEPACOFEN 100 mg S.R. | 100 mg | Once or twice daily |
| MEPACOFEN L.A. 150 mg | 150 mg | Once daily |
| MEPACOFEN Gel | 2.5% | Apply 2-3 times daily |
Children
Not recommended unless specifically prescribed by a doctor. Safety and efficacy in children have not been firmly established for all forms.
Special Populations
- Elderly: May require a lower dose due to increased sensitivity or kidney concerns.
- Patients with kidney/liver issues: Should use with caution; consult a doctor first.
- Pregnant or breastfeeding women: Should avoid unless approved by a healthcare provider.
Side Effects and Management
Like all medications, MEPACOFEN may cause side effects. Most are mild and temporary, but some may require medical attention.
Common Side Effects
- Stomach upset
- Nausea
- Dizziness
- Headache
Less Common Side Effects
- Heartburn
- Rash (with gel use)
- Photosensitivity (sensitivity to sunlight)
Serious but Rare Side Effects
- Stomach bleeding
- Severe skin reactions
- Kidney problems
What to Do:
- For mild side effects, rest and stay hydrated.
- Avoid using on an empty stomach to reduce gastric upset.
- If a rash or severe pain occurs, stop using the product and contact a doctor.
Warnings and Precautions
| Warning Category | Details |
|---|---|
| Stomach Issues | Can cause ulcers or bleeding, especially in long-term use |
| Kidney Problems | May worsen kidney function in sensitive individuals |
| Heart Conditions | Prolonged use may increase heart attack or stroke risk |
| Pregnancy | Avoid during the last trimester unless doctor-approved |
| Allergic Reactions | Can cause asthma attacks or skin rashes in allergic individuals |
| Photosensitivity | Topical form may increase skin's reaction to sunlight |
| Children/Elderly | Use under strict medical supervision only |
Always read the leaflet and discuss any medical history with your doctor before starting MEPACOFEN.
Drug Interactions
MEPACOFEN can interact with several medications. These interactions can either reduce effectiveness or increase the risk of side effects.
Potential Interactions
- Blood thinners (e.g., Warfarin) – increased bleeding risk
- Other NSAIDs or aspirin – higher chance of stomach issues
- Blood pressure medications – may reduce effectiveness
- Diuretics (water pills) – may affect kidney function
- Methotrexate – increased toxicity risk
- Lithium – risk of lithium buildup in the blood
Always inform your doctor about all medications, supplements, and herbal products you are taking.
Case Studies
Case 1: Relief After Sports Injury
Situation: A 25-year-old man sprained his ankle during a soccer match. Treatment: He applied MEPACOFEN 2.5% gel 3 times daily for 5 days. Result: Swelling and pain reduced significantly, and he returned to training within a week.
Case 2: Managing Arthritis in Elderly
Situation: A 67-year-old woman with osteoarthritis in the knees. Treatment: Prescribed MEPACOFEN L.A. 150 mg once daily. Result: Improved mobility and less morning stiffness after 10 days.
Frequently Asked Questions (FAQs)
1. What is MEPACOFEN used for? It is used to relieve pain, swelling, and inflammation in conditions like arthritis, back pain, injuries, and menstrual cramps.
2. Is MEPACOFEN safe during pregnancy? Avoid in the third trimester. Consult your doctor before use.
3. Can I take MEPACOFEN with other painkillers? Avoid combining with other NSAIDs or aspirin unless instructed by a doctor.
4. What if I miss a dose? Take it as soon as you remember. If it's close to your next dose, skip it. Do not double the dose.
5. Can I drive after taking MEPACOFEN? Yes, unless you feel dizzy or sleepy. Then it's better to avoid driving.
6. How do I store MEPACOFEN? Store in a cool, dry place, away from direct sunlight and out of reach of children.
7. Can children use MEPACOFEN? Use only under a doctor’s guidance. Not typically recommended for children.
8. How soon does MEPACOFEN work? Pain relief usually starts within 1 hour for tablets and capsules; within 30 minutes for the gel.
9. Is the topical gel as effective as the tablets? It is effective for localized pain but not suitable for systemic conditions like arthritis.
10. Does MEPACOFEN cure inflammation? It controls symptoms, but it does not cure the underlying disease.
Conclusion
MEPACOFEN is a trusted and effective option for managing a variety of painful and inflammatory conditions. Available in multiple forms — from tablets to topical gel — it offers flexibility and convenience for many users.
Whether you're dealing with joint pain, muscle injuries, or menstrual cramps, MEPACOFEN provides fast relief when used correctly. Remember to follow the dosage guidelines, watch for side effects, and talk to your healthcare provider if you have any concerns.
Stay informed, stay safe — and never self-medicate without guidance.
About the Author
Dr. Ahmad Baker, PharmD
He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.
Legal Disclaimer
The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.
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