Adol PM Caplets, Granules for Hot Therapy (in Sachets): A Comprehensive Guide
Adol PM Caplets, Granules for Hot Therapy (in sachets) is a therapeutic product designed to provide temporary relief from night-time pain and difficulty sleeping. This medication combines the analgesic and antipyretic effects of paracetamol with the sedative properties of diphenhydramine hydrochloride. Below, we delve into its composition, indications, dosage, potential side effects, and more.
Introduction
Adol PM Caplets, Granules for Hot Therapy (in sachets) are formulated to help alleviate discomfort caused by minor aches, headaches, coughs, colds, and fever, especially when these symptoms interfere with sleep. The caplets are easy to swallow due to their special coating, while the granules offer an alternative option for those who prefer or require it, providing rapid absorption and effective relief through "hot therapy."
Composition
Caplets
Each Adol PM Caplet contains:
- Active ingredients:
- Paracetamol 325mg [an analgesic and antipyretic that works by elevating the pain threshold centrally and blocking pain-impulse generation peripherally]
- Diphenhydramine HCl 25mg [an ethanolamine antihistamine with sedative and anticholinergic properties]
- Excipients: Cellulose, stearic acid, magnesium stearate, cross-linked starch, starch, povidone, aerosil, glycerol, gelatin, hypromellose, polyethylene glycol, titanium dioxide, FD&C blue 1, FD&C blue 2, and talc.
Granules for Hot Therapy (in Sachets)
Each sachet of Adol PM Granules for Hot Therapy contains:
- Active ingredients:
- Paracetamol 650mg [an analgesic and antipyretic]
- Diphenhydramine HCl 50mg [an antihistamine with sedative properties]
- Excipients: Sucrose, aspartame [a low-calorie sweetener], citric acid, sodium citrate, sodium chloride, starch, D&C yellow 10, FD&C red no. 40, lemon dry flavor, and honey dry flavor.
Indications
Adol PM Caplets, Granules for Hot Therapy (in sachets) are used for the temporary relief of night-time pain associated with difficulty sleeping. This includes pain due to cough, cold, headache, minor aches, and fever.
Warnings/Precautions
When Should You Avoid Using Adol PM?
- If you are sensitive to paracetamol, diphenhydramine, or any of the excipients.
- If you suffer from severe liver disease, since sedation may be inappropriate.
What Should You Be Aware Of?
- Do not take more than 2 caplets at one time.
- Other products containing paracetamol may be taken for daytime pain relief, but the total maximum dose should not exceed 4 grams in 24 hours. Further doses of paracetamol should not be taken within 4 hours of a dose of Adol PM.
- Do not use this medicine for more than 7 consecutive nights without consulting your doctor.
- Do not give to children below 12 years old without consulting your doctor or pharmacist.
- Be cautious if you are alcoholic or if you suffer from epilepsy, glaucoma, pyloroduodenal obstruction, mild to moderate liver disease, kidney dysfunction, prostatic enlargement, or urinary retention.
- Since Adol PM contains diphenhydramine, it may cause drowsiness; therefore, be aware when driving motor vehicles or operating hazardous machinery.
- It is recommended to stop using Adol PM at least 72 hours before performing skin tests for allergy due to possible false-negative results.
- Pregnancy: Although there are no known risks associated with the use of the active ingredients during pregnancy, it is better not to use unless your doctor tells you to.
- Lactation: As it is assumed that diphenhydramine may inhibit breastfeeding, as well as it may be secreted in breast milk, this medicine is better not to be used unless your doctor tells you to.
- Individuals suffering from phenylketonuria or those who should avoid protein foods should use Adol PM sachets with caution due to the presence of phenylalanine in the excipient aspartame.
Dosage and Administration
Adults and Children Over 12 Years:
Take 2 caplets or one sachet about 20 minutes before bedtime.
For "Hot Therapy" Sachets:
Tear or cut open the sachet as indicated. Dissolve the contents of one sachet in a 6-ounce (180mL) cup of hot water. Sip while hot. If desired, sweeten to taste.
Side Effects
Side effects are usually mild and infrequent. However, some people may rarely feel more alert, especially with high doses or in the elderly. Other side effects which have been reported less frequently include:
- Headache
- Difficulty of muscle coordination
- Difficulty in passing urine
- Dry mouth
- Blurred vision
- Gastrointestinal disturbances
Hypersensitivity reactions including swelling of the face, lips, mouth, tongue or throat, thickened phlegm, chest tightness, anaphylaxis, rashes, and sensitivity of skin to sunlight have also been reported less frequently.
Very rarely, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, palpitations, changes to heart rhythm, low blood pressure, blood disorders, liver dysfunction, and extrapyramidal effects have been reported.
Drug Interactions
Talk to your doctor or pharmacist if you are taking any other medicines, particularly:
- Alcohol, anxiolytics, and hypnotics, as they may intensify the sedative effect of Adol PM.
- Anticholinergics (antimuscarinics), as they may enhance the anticholinergic side effects.
- Antidepressants (monoamine oxidase inhibitors and tricyclic antidepressants), as they may enhance both the sedative and the anticholinergic effects of Adol PM.
- Betahistine (histamine analogue), as it is expected to antagonize the effects of Adol PM.
- Cholestyramine (used to treat high blood cholesterol), as it may reduce the absorption of paracetamol.
- Metoclopramide (used to treat nausea and vomiting), as it increases the rate of absorption of paracetamol.
- Coumarins (anticoagulants): Occasional doses of paracetamol may be taken. If you need to take painkillers on a daily basis over a long period, talk to your doctor.
- Intravenous busulfan (used to treat leukemia) should be used with caution if administered within 72 hours of taking paracetamol, as paracetamol may possibly inhibit its metabolism.
Latest Information
Adol PM Caplets, Granules for Hot Therapy (in sachets) is produced by Julphar Gulf Pharmaceutical Industries in Ras Al Khaimah, U.A.E. The product is available in packs of 24 caplets and 6 sachets. Store at a temperature not exceeding 25°C, in a dry place.
For any inquiries, call the toll-free number (971) 800-4994.
Conclusion
Adol PM Caplets, Granules for Hot Therapy (in sachets) offers effective relief from night-time pain and difficulty sleeping. By following the prescribed dosage and being aware of potential interactions and side effects, users can safely utilize this medication to improve their quality of rest. Always consult with a healthcare professional for personalized advice and guidance.
Adol PM Caplets, Granules for Hot Therapy (in sachets) Leaflet
Adol PM - Gulf Pharmaceutical Industries - Julphar
Gulf Pharmaceutical Industries - Julphar, is the company that owns the production and marketing rights for Adol PM, and it is an Emirati company. For more information or to inquire about the properties of this product or its availability in your country of residence, or to report defects or side effects related to this pharmaceutical product, you can contact one of the offices of Gulf Pharmaceutical Industries - Julphar by phone, fax, or email, from the link here.
About the Author
Dr. Ahmad Baker, PharmD
He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.
Legal Disclaimer
The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.
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