Understanding Guaphan DM Syrup: A Comprehensive Guide to Its Uses and Safety

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 Guaphan DM Syrup is a medication designed to temporarily relieve coughs caused by minor throat and bronchial irritation, such as those associated with the common cold. It also helps loosen phlegm (mucus) and thin bronchial secretions, making coughs more productive. This blog post provides detailed information about its composition, indications, precautions, dosage, side effects, and other relevant details.



Composition

Each 5 ml of Guaphan DM Syrup contains:

  • Guaifenesin (EP) 100 mg: An expectorant that reduces the adhesiveness and surface tension of respiratory tract secretions, easing their expectoration [the act of expelling mucus or phlegm from the respiratory system].
  • Dextromethorphan Hydrobromide (USP) 10 mg: A centrally acting antitussive that elevates the threshold for coughing without inhibiting ciliary activity [tiny hair-like structures in the respiratory tract that help move mucus out].

Clinical Pharmacology

Guaifenesin works by reducing the adhesiveness and surface tension of respiratory tract secretions, thereby facilitating their removal. The expectorant effect can reduce the frequency of coughs. Dextromethorphan Hydrobromide acts centrally to increase the threshold for coughing, ensuring that therapeutic dosages do not interfere with the normal function of cilia [hair-like structures in the respiratory tract that help clear mucus].

Indications

Guaphan DM Syrup is used to temporarily relieve coughs due to minor throat and bronchial irritation, such as those occurring during a cold. It also aids in loosening phlegm (mucus) and thinning bronchial secretions, making coughs more productive.

Warnings and Precautions

  • Do not use this product if you are hypersensitive to any of the ingredients.
  • This medication should not be used for treating cough and cold symptoms in children under 6 years of age.
  • Avoid using Guaphan DM Syrup for persistent or chronic coughs, such as those associated with smoking, asthma [a chronic respiratory condition characterized by inflammation and narrowing of the airways], chronic bronchitis [long-term inflammation of the bronchi], emphysema [a lung condition causing shortness of breath], or if the cough is accompanied by excessive phlegm (mucus), unless directed by a physician.
  • A persistent cough may indicate a serious condition. If the cough persists for more than one week, tends to recur, or is accompanied by fever, rash, or a persistent headache, consult a physician.
  • Do not use this product if you are currently taking a prescription monoamine oxidase inhibitor (MAOI) [a class of drugs used for depression, psychiatric conditions, or emotional disorders] or have taken one within the past two weeks. If you are unsure whether your prescription drug contains an MAOI, consult a physician before using this product.

Dosage and Administration

  • Adults and children 12 years and over: 10 ml every 4 hours.
  • Children 6 years to under 12 years: 5 ml every 4 hours.
  • Do not exceed 6 doses in a 24-hour period.

Side Effects

Potential adverse reactions include drowsiness [feeling sleepy], dizziness [a sensation of lightheadedness or unsteadiness], and gastrointestinal disturbances [issues related to digestion, such as nausea or stomach discomfort].

Use During Pregnancy and Lactation

As with any medication, if you are pregnant or nursing a baby, seek advice from a physician before using Guaphan DM Syrup.

Storage

Store at room temperature (15-25°C). Do not use the drug after the expiry date printed on the package.

Latest Information

Guaphan DM Syrup is manufactured by Riyadh Pharma, Medical and Cosmetic Products Co. Ltd., located in Riyadh, Saudi Arabia. The leaflet was last revised in June 2011. For any side effects or quality issues, contact the National Pharmacovigilance Center via fax (+966-1-205-7662), email (npc.drug@sfdagov.sa), or website (www.sfda.gov.sa/npc).

Conclusion

Guaphan DM Syrup is an effective solution for relieving coughs and aiding in the removal of mucus. However, it is essential to follow the prescribed dosage and heed all warnings and precautions to ensure safe and effective use. Always consult a healthcare professional if you have concerns or experience persistent symptoms.
 
   
     

About the Author

     

Dr. Ahmad Baker, PharmD

     

He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.

   
   
      Dr. Ahmad Baker    
 
      
   

Legal Disclaimer

   

The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.

 

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