Zetamibe Tablets: Ezetimibe for Cholesterol Reduction

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Composition:

Each scored tablet contains: Ezetimibe 10 mg.

Properties:

Ezetimibe appears to act at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the blood. Zetamibe reduces total-C, LDL-C, Apo B, and TG, and increases HDL-C in patients with hypercholesterolemia. Administration of Zetamibe with an HMG-CoA reductase inhibitor shows better results than either treatment alone.

Indications:

  • Primary hypercholesterolemia (heterozygous familial and nonfamilial), as monotherapy or in combination with an HMG-CoA reductase inhibitor to reduce elevated cholesterol, low-density lipoproteins, and triglycerides, in adjunction to diet.
  • In patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments.

Dosage Administration:

Generally, the recommended dose is one tablet of Zetamibe once daily, with or without food. Zetamibe may be administered with an HMG-CoA reductase inhibitor (at the same time of the day) for incremental effect.

Contra Indications:

  • Hypersensitivity to any component of this medication.
  • The use of Zetamibe with HMG-CoA reductase inhibitors is contraindicated with active liver disease or unexplained persistent elevations of serum transaminases.

Side Effects:

The Drug is generally well tolerated.

Packing:

Box contains 10 scored tablets in one strip.

Zetamibe is a product manufactured by Adwia Pharmaceuticals Industries. Adwia is a leading Egyptian company founded in 1984 with a mission to bring the latest technologies and the highest available know-how to the market. They are committed to innovation and care and have a proven track record of success. For more information about Adwia Pharmaceuticals Industries, please visit their website or contact them directly.

 
   
     

About the Author

     

Dr. Ahmad Baker, PharmD

     

He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.

   
   
      Dr. Ahmad Baker    
 
      
   

Legal Disclaimer

   

The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.

 

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