Understanding Isoptin® 240 mg SR Tablets

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In this guide, we'll break down important information about Isoptin® 240 mg SR Tablets, making it easy for everyone to understand. This medication, primarily for hypertension treatment and secondary prevention after a heart attack, contains the active substance Verapamil hydrochloride.

About Isoptin® 240 mg SR Tablets

What is Isoptin®?

Isoptin® is a calcium antagonist designed to treat hypertension (high blood pressure) and provide secondary prevention after an acute myocardial infarction (heart attack). It works by inhibiting the influx of calcium ions into the heart and vascular smooth muscle cells, leading to reduced peripheral vascular resistance without a significant increase in heart rate.

How Isoptin® Works

Isoptin® has several effects on the cardiovascular system:

  • Antihypertensive Effect: Decreases peripheral vascular resistance.
  • Myocardial Blood Flow: Enhances blood flow to the heart muscles.
  • Antiarrhythmic Effect: Especially in supraventricular arrhythmias, it delays impulse conduction in the AV node and decreases ventricular rate.

Indications: When is Isoptin® Prescribed?

  • Hypertension: For all types of hypertension, it can be used alone or in combination with other antihypertensive drugs.
  • Secondary Prevention after Heart Attack: Reduces the risk of further cardiovascular events after a heart attack.

Dosage and Administration

Isoptin® SR 240 mg tablets are to be taken regularly as prescribed by the physician. The usual dose is one tablet in the morning, with the option to increase to a maximum of two tablets daily if needed. The tablet should be swallowed whole with liquid, preferably with or shortly after meals.

In cases of impaired hepatic function, dosage should be adjusted carefully, starting with the lowest possible dose.

Contraindications: When Not to Use Isoptin®

Isoptin® SR 240 mg should not be given in certain cases:

  • Cardiovascular shock.
  • Complicated acute myocardial infarction (marked bradycardia, hypotension, left ventricular failure).
  • Severe conduction disorders (2nd and 3rd-degree AV block) and sick sinus syndrome.

Side Effects: What to Watch For

Common side effects include constipation, while rare effects may include nausea, vertigo, headache, and allergic skin reactions. Some cardiovascular effects may occasionally be greater than desired, such as bradycardiac arrhythmias or hypotension, especially at high doses or in the presence of previous damage.

Interactions with Other Medications

Isoptin® may interact with various drugs, including beta-receptor blockers, antiarrhythmics, inhalation anesthetics, and others. Special caution is advised when combining Isoptin® with specific medications, and your healthcare provider should be informed of all medications you are taking.

Precautions and Safety Measures

  • Blood pressure monitoring is essential during Isoptin® treatment.
  • Individual susceptibility may affect the ability to drive or operate machinery, especially initially and when changing from another drug.
  • Isoptin® should not be given during pregnancy (especially in the first trimester) and lactation unless essential for the patient’s well-being.

Conclusion

Isoptin® 240 mg SR Tablets play a crucial role in managing hypertension and preventing further cardiovascular issues after a heart attack. Understanding its indications, dosage, potential side effects, and interactions is vital for patients. Always follow your healthcare provider's guidance, and if you experience any concerning symptoms, consult your healthcare professional promptly. This guide aims to empower you with knowledge, but it's not a substitute for professional medical advice.

 
   
     

About the Author

     

Dr. Ahmad Baker, PharmD

     

He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.

   
   
      Dr. Ahmad Baker    
 
      
   

Legal Disclaimer

   

The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.

 

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