Unlocking Vital Information: EREC® Tablets for Erectile Dysfunction

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EREC® Tablets, each containing 100mg of Sildenafil, serve as a potent solution for erectile dysfunction. This comprehensive guide navigates through EREC®, covering its composition, mechanism of action, indications, dosages, contraindications, potential side effects, drug interactions, precautions, and storage guidelines.

Composition and Mechanism of Action

Composition:

  • Each tablet contains 100mg Sildenafil.

Mechanism of Action:

  • Sildenafil, a phosphodiesterase inhibitor, competitively inhibits phosphodiesterase enzyme type 5.
  • Inhibition of this enzyme increases cyclic guanosine monophosphate (cGMP), a mediator of vasodilation, leading to relaxation of corpus cavernosal smooth muscles.
  • Increased blood flow into cavernosal spaces results in heightened intra-cavernosal pressure, a key factor in achieving an erection.

Indications

Indication:

  • Treatment of Erectile Dysfunction.

Dosages

  1. Adult Dosage:

    • Half tablet (50mg Sildenafil) orally before sexual activity.
    • Can be taken anytime between half to four hours before sexual activity.

  2. Dosage Range:

    • 25mg to 100mg daily, with a maximum frequency of once daily.

  3. Special Considerations:

    • A 25mg dose for patients with hepatic impairment, severe renal failure, or age over 65.

Contraindications

  1. Nitrates:

    • Contraindicated in patients using organic nitrates due to potential hypotensive effects.

  2. Cardiovascular Conditions:

    • Caution advised for patients with preexisting cardiovascular diseases where sexual activity is inadvisable.

  3. Vision Disturbances:

    • Contraindicated in patients with retinal nerve atrophy or any vision disturbances.

  4. Hypersensitivity:

    • Avoid in case of hypersensitivity to Sildenafil or any tablet component.

  5. Priapism:

    • Immediate medical assistance needed for prolonged erection (>4 hours) or painful erection (>6 hours).

Side Effects

  1. Body-Wide:

    • Face edema, headache, photosensitivity reactions, allergic reactions, chest pain, visual changes, and transient increased brightness.

  2. Cardiovascular:

    • Angina, syncope, tachycardia, hypotension, heart failure, flushing.

  3. Hematologic & Musculoskeletal:

    • Anemia, leukopenia, myalgia, arthritis, tendon rupture.

  4. Neurological:

    • Tremor, vertigo, depression, insomnia, abnormal dreams, ataxia.

  5. Dermatologic:

    • Urticaria, pruritus, sweating, skin ulcer, contact dermatitis.

  6. Special Senses:

    • Mydriasis, conjunctivitis, deafness, eye hemorrhage, cataract, dry eye.

  7. Digestive & Genitourinary:

    • Vomiting, dysphagia, gastritis, urinary frequency, breast enlargement, abnormal ejaculation.

Drug-Drug Interactions

  • Interacts with Cimetidine, erythromycin, ketoconazole, itraconazole, ritonavir, darunavir, increasing Sildenafil levels.
  • Rifampicin decreases Sildenafil serum level.

Precautions

Use with caution in patients with:

  1. Recent cardiovascular events.
  2. Resting hypotension or hypertension.
  3. Cardiac failure or coronary artery disease.
  4. Anatomical deformation of the penis.
  5. Sickle cell anemia, multiple myeloma, or leukemia.
  6. Retinitis pigmentosa.
  7. Bleeding disorders or active peptic ulceration.

Storage and Packaging

  • Store below 30°C, away from direct sunlight, and out of reach of children.
  • Packaging: Boxes containing 1, 3, 25, 50, or 100 strips, each with 1, 2, or 4 tablets and an insert.

Conclusion

EREC® Tablets with Sildenafil 100mg offer a targeted solution for erectile dysfunction. Medical practitioners are urged to follow recommended dosages, consider contraindications, and monitor potential side effects, ensuring optimal patient safety and efficacy.

 
   
     

About the Author

     

Dr. Ahmad Baker, PharmD

     

He is a senior pharmacist and health educator with extensive experience in the Middle East and North Africa region. Through his writing, Dr. Ahmad aims to empower communities by providing reliable, evidence-based health information. With expertise in clinical pharmacy and regulatory affairs, he strives to offer unique insights into healthcare and simplify complex medical concepts, making them accessible to everyone.

   
   
      Dr. Ahmad Baker    
 
      
   

Legal Disclaimer

   

The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice. We do not guarantee the accuracy or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. By using this blog, you agree to assume personal responsibility for relying on the information provided.

 

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