Olapex F.C. Tablets - Olanzapine - Antipsychotic agent.

-

 COMPOSITION

  • Olapex 5 mg: Olanzapine 5 mg.
  •  Olapex 10 mg: Olanzapine 10 mg.

PROPERTIES

Olanzapine has shown a broad pharmacological effect across a number of receptor systems. Olanzapine demonstrates greater affinity for serotonin receptors as well as dopamine receptors. 

Olanzapine is well absorbed after oral administration and reaches peak plasma concentration within 6 hours. The absorption is not affected by food. Olanzapine is metabolized in the liver and the mean terminal half-life is 30 hours.

INDICATIONS

  • Olanzapine is indicated for acute and maintenance treatment of short term schizophrenia and other psychosis where positive and / or negative symptoms are prominent. 
  • Olanzapine also alleviates the secondary disorders.

DOSAGE & ADMINISTRATION

The recommended daily dose is 10 mg once daily adjusted to usual range 5-20 mg daily. 

Doses of 15 mg or greater should be given only after reassessment. 

Starting dose of 5 mg per day is considered for geriatric patients and patients with severe renal or moderate hepatic impairment.

CONTRAINDICATIONS

  • Patients with known hypersensitivity to olanzapine.
  • Angle closure glaucoma. Breast-feeding.
  • Pregnancy use only if potential benefit outweighs risk.

WARNINGS AND PRECAUTIONS

In neuroleptic malignant syndrome and tardive dyskinesia, discontinuation of all antipsychotic drugs including olanzapine is required.

Use in specific population: Pregnancy (Non-teratogenic effects): This product should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

withdrawal symptoms following delivery. There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence.

Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or respiratory distress and feeding disorder in these neonates. These complications have varied in severity, while in some cases symptoms have been self-limited; in other cases neonates have required intensive care unit support and prolonged hospitalization.

Olanzapine should be used with caution in patients with:

  • Hepatic impairment. 
  • Anticholinergic drugs.
  • Centrally acting drugs.
  • Alcohol.
  • Prostatic hypertrophy.
  • Paralytic ileus.
  •  Low leukocyte or neutrophil count.
  • Bone marrow depression.
  • Hypereosinophilic disorders
  • Myeloproliferative disease.
  • Concomitant administration of drugs that prolong QT interval (especially in elderly).
Increase chance of death in elderly patient with dementia-related.

SIDE EFFECTS

Weight gain, somnolence, dizziness, akathisia, constipation, dry mouth, orthostatic hypotension and peripheral edema are occasionally seen with olanzapine, blood dyscrasia, transient asymptomatic elevations of liver enzymes.



PACKAGE AND STORAGE

  • Olapex 5 mg: Pack of 30 F.C. Tablets.
  • Olapex 10 mg: Pack of 30 F.C. Tablets. 
  • Store at temperature not exceeding 30 C..
  • Keep All Medicines Out of Reach of Children
  • Manufactured by: Apex Pharma - S.A.E- Badr City - Egypt. 

Comments

Post a Comment

Popular posts from this blog

Pharmaceutical Companies and Agencies in Bahrain

-
Bahrain is home to several pharmaceutical companies and agencies that play a significant role in the healthcare industry. These companies contribute to the availability of medications and healthcare products in the country. In this blog post, we will explore some of the top pharmaceutical companies in Bahrain and discuss the regulatory authority responsible for ensuring the quality and safety of pharmaceutical products. Top Pharmaceutical Companies in Bahrain Gulf Biotech : Gulf Biotech is one of the leading pharmaceutical companies in Bahrain. They focus on the research, development, and manufacturing of innovative medicines and healthcare products. Hamad Town Pharmacy Group : Hamad Town Pharmacy Group is a well-established pharmaceutical company in Bahrain. They provide a wide range of pharmaceutical products and services to meet the healthcare needs of the population. Wael Pharmacy : Wael Pharmacy is a trusted name in the pharmaceutical i
Read more

Understanding the Prohibition of Eating Donkey Meat in Islam

-
Image
In Islam, the consumption of donkey meat is considered haram or prohibited. This article delves into the reasons behind this prohibition, citing various Hadiths that explicitly forbid the consumption of donkey meat. It also explores the differing opinions among scholars regarding the permissibility of eating the meat of wild donkeys. Additionally, the article emphasizes the importance of seeking guidance from knowledgeable scholars in matters of Islamic jurisprudence. The Prohibition of Donkey Meat in Islam According to Islamic teachings, eating donkey meat is considered impermissible due to specific Hadiths that categorically forbid it. The Prophet Muhammad (peace be upon him) is reported to have stated, "It is not permissible to eat the meat of domesticated donkeys." This prohibition is rooted in the prophetic traditions and serves as a clear guideline for Muslims regarding dietary restrictions. Moreover, the prohibition of consuming donkey meat extends to the flesh o
Read more

Unleashing the Power of Stimulan: Your Guide to Improved Brain Function

-
In the realm of cognitive well-being, understanding medications that enhance intellectual functions is key to unlocking improved brain performance. Stimulan, a neurotropic drug , has been designed to act on the cerebrum, enhancing cerebral blood flow and neuronal effects. In this comprehensive guide, we will delve into what Stimulan is, how it works, when to use it, and essential precautions to ensure a safe and effective journey toward improved cognitive function. Decoding Stimulan: What's Inside? Stimulan comes in various forms, including capsules, tablets, syrup, and ampoules, each containing the active ingredient, piracetam. Piracetam, at its core, is a neurotropic drug that influences the cerebrum, particularly the hippocampus, through both vascular and neuronal effects. Understanding How Stimulan Works Stimulan's vascular effect improves cerebral blood flow without causing vasodilation, a process crucial for maintaining optimal brain function. It enhances red blood ce
Read more