CARVID 6.25 mg and 25 mg tablets

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Composition

Each tablet contains carvedilol 6.25 mg or 25 mg.

PROPERTIES

Carvedilol, the active ingredient in CARVID, is a cardioprotective non cardio selective beta adrenoceptor blocking drug (beta-blocker) which has in addition an arteriolar vasodilating action by alpha 1 receptor blocking effect, and thus lowers peripheral resistance.

INDICATIONS

1 • .Essential hypertension.
2 • Angina pectoris.
3 • Chronic heart failure adjunct to diuretics, digoxin, or ACE inhibitors.
4• Left ventricular dysfunction following acute myocardial infarction.

DOSAGE AND ADMINISTRATION

Hypertension: Initially 12.5 mg once daily or individualized increased after 3 days to the usual dose 25 mg once daily or individualized. If necessary may be further increased at intervals of at least 7 to 14 days to maximum daily dose of 50 mg given once a day or in divided doses. The full antihypertensive effect of CARVID is seen within 7 to 14 days.

Angina pectoris: Initially 12.5 mg twice daily, increased after 2 days to 25 mg twice daily.

Heart failure: Dosage must be individualized and closely monitored by a physician during up-titration. Prior to initiation of CARVID, it is recommended that fluid retention be minimized. The recommended starting dose of CARVID is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive intervals of at least 2 weeks. Patients should be maintained on lower doses if higher doses are not tolerated. A maximum dose of 50 mg twice daily has been administered to patients with mild to moderate heart failure weighing over 85 kg.

Left ventricular dysfunction following myocardial infarction: Dosage must be individualized and monitored during up-titration. Treatment with CARVID may be started as an inpatient or outpatient and should be started after the patient is hemodynamically stable and fluid retention has been minimized. It is recommended that CARVID be started at 6.25 mg twice daily and increased after 3 to 10 days, based on tolerability, to 12.5 mg twice daily, then again to the target dose of 25 mg twice daily. A lower starting dose may be used (3.125 mg twice daily) and/or the rate of up-titration may be slowed if clinically indicated.

SIDE EFFECTS

Low blood pressure which may cause dizziness, headaches and fatigue which are normally mild occurs at the beginning of treatment. Slow heartbeats, tiredness, shortness in breath in patients with tendency to bronchospastic reaction, may hide some of symptoms of low blood sugar manifested by other beta-blocker (fast heart beat). 

Exacerbation of symptoms in-patient with Raynaud's disease. Gastrointestinal upset with symptoms such as nausea, abdominal pain, diarrhea, constipation and vomiting.

WARNINGS AND PRECAUTIONS

1 • CARVID should not be administered to patients not permitted to use adrenergic blocking agents.
2 • Avoid abrupt withdrawal in angina.
3 • Avoid in pregnancy & breast-feeding.
4•  Heart failure should be controlled with appropriate therapy before CARVID is initiated and the patient should be closely monitored after each dose increase.
5 • Avoid or caution to be exercised with hepatic impairment. 
6 •  Avoid or caution to be exercised with renal impairment.

DRUG INTERACTIONS

Antihypertensives: enhanced hypotensive effect; increased risk of withdrawal hypertension with clonidine (withdraw beta-blocker several days before slowly withdrawing clonidine). 

Cardiac glycosides: increased AV block and bradycardia.

Conduction disturbance (rarely with hemodynamic compromise) has been observed when carvedilol is coadministered with diltiazem.

CONTRAINDICATIONS

Carvedilol must not be used in patients with:
1 • Hypersensitivity to carvedilol or any component of the product. 
2 • Unstable/decompensated heart failure.
3 • Clinically manifest liver dysfunction.
4 • 2nd and 3rd degree AV block (unless a permanent pace maker is in place). Severe bradycardia (< 50 bpm).
5 • Sick sinus syndrome (including sino-atrial block).
6 • Severe hypotension (systolic blood pressure < 85 mmHg).
7 • Cardiogenic shock.
8 • Bronchial asthma or related bronchospastic conditions.
  • Store in a dry place at temperature below 30 °C.
  • Keep All Medicines Out of Reach of Children
  • Manufactured by: Apex Pharma - S.A.E - Badr City- Egypt.

المزيد من المعلومات عن كارفيد

كارفيد لعلاج ضغط الدم ولحماية عضلة القلب - كارفيديلول

كارفيد يعمل عن طريق منع و أيقاف عمل  مواد طبيعية معينة في الجسم، مثل مادة ادرينالين، على القلب والأوعية الدموية. وهذا التأثير المضاد للأدرينالين يعمل على خفض ضغط الدم و يقلل من معدل ضربات القلب. كَارفِيديلول هو المُكون النشط في دواء كارفيد، وهو عقار ينتمي إلى فئة من العقاقير تعرف باسم حاصرات مستقبلات البيتا والألفا.

يستخدم كارفيد لعلاج ارتفاع ضغط الدم ولعلاج فشل القلب. فشل القلب هو حالة تعجر فيها عضلة القلب عن ضخ الدم بشكل جيد. كارفيد يساعد عضلة القلب على ضخ الدم بشكل جيد مما يساهم فى تحسين أسلوب الحياة و خصوصا للمرضى الذين سبقت اصابتهم بأزمات قلبية. أيضًا يخفض كارفيد ضغط الدم المرتفع، مما يساهم فى الوقاية من الاصابة بالسكتات الدماغية والنوبات القلبية، والمشاكل في الكليتين و غيرها من المشاكل التى يمكن ان تنتج نتيجة ارتفاع ضغط الدم.

يمكن أيضا أن  يستخدم كارفيد لعلاج نوع معين من عدم انتظام ضربات القلب (الرجفان الأذيني). يتوافر كارفيد في عدة عيارات لتناسب الحالات المختلفة المستهدفة بالمعالجة... تابع القراءة

كارفيد لعلاج ضغط الدم المرتفع وتنظيم إيقاع القلب

يستخدم كارفيد بشكل منفرد أو جنبا إلى جنب مع أدوية أخرى لعلاج ارتفاع ضغط الدم (ضغط الدم المرتفع)، و تنبع أهمية خفض ارتفاع ضغط الدم فى أنة يساعد على منع السكتات الدماغية والنوبات القلبية، كما أن ضغط الدم المرتفع قد يؤدى إلى مشاكل خطيرة في الكلى إذا لم تتم السيطرة علية. لذلك فأن خفض ضغط الدم يقى من الإصابة بمشكلات الكلى المرتبط بارتفاع ضغط الدم .

يستخدم كارفيد أيضا لعلاج ألم الذبحة الصدرية، وتحسين نوعية الحياة بعد الاصابه بأزمة قلبية.... تابع القراءة

كارڤيد دواء لحمايـة عضلة القلب ولمعالجة إرتفاع ضغط الدم

يستخدم كارڤيد لعلاج قصور القلب، وهى حالة لا يستطيع فيها القلب ضخ ما يكفي من الدم إلى جميع أجزاء الجسم، كما يُوصف كارڤيد إيضًا لمعاجة ارتفاع ضغط الدم. كما أنه يستخدم لعلاج الأشخاص الذين أصيبوا بنوبة قلبية. غالبًا ما يستخدم كارڤيد مع أدوية أخرى. كارفيديلول، هو المكون النشط في دواء كارڤيد، وهو عقار ينتمي إلى فئة من الأدوية تسمى حاصرات مستقبلات البيتا، ويعمل عن طريق إرخاء الأوعية الدموية وإبطاء معدل ضربات القلب لتحسين تدفق الدم وخفض ضغط الدم... تابع القراءة

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